Rule-based systems can aid physicians in many different areas, including diagnosis and treatment. An example of a rule-based expert system in the clinical setting is MYCIN. Developed at Stanford in the 1970s, MYCIN was based on around 600 rules and was used to help identify the type of bacteria causing an infection. While useful, MYCIN can help to demonstrate the magnitude of these types of systems by comparing the size of the rule base (600) to the narrow scope of the problem space.
The Stanford AI group subsequently developed ONCOCIN, another rules-based expert system coded in Lisp in the early 1980's
from http://en.wikipedia.org/wiki/Clinical_decision_support_system#Rule-Based_System